[Modelling of the epidemic process of suppurative septic infections using a Pseudomonas aeruginosa bacteriophage]

Area of Science:

• Microbiology
• Epidemiology
• Infectious Disease Control

Background:

• Pyoseptic infections pose a significant threat in healthcare settings.
• Understanding transmission routes is crucial for effective control strategies.

Purpose of the Study:

• To propose a novel method for modeling pyoseptic infection epidemics.
• To investigate the role of bacteriophage therapy in managing these infections.
• To identify key transmission vectors within hospital environments.

Main Methods:

• Development of an epidemic process model incorporating P. aeruginosa bacteriophage.
• Application of the model in clinical settings, specifically urological and traumatological wards.
• Data analysis to confirm infection sources and transmission pathways.

Main Results:

• The proposed modeling method effectively simulates pyoseptic infection dynamics.
• Patients were confirmed as primary sources of P. aeruginosa infections.
• Medical instruments and healthcare personnel hands were identified as significant vectors for pathogen transfer.

Conclusions:

• The developed model provides a valuable tool for understanding and managing pyoseptic infections.
• Targeting patient-related factors and improving hygiene practices for instruments and staff are essential for infection control.
• Bacteriophage therapy presents a potential avenue for combating P. aeruginosa outbreaks.