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Updated: Jan 25, 2026
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Isolation and Characterization of RNA-Containing Exosomes
Published on: January 9, 2012
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The State of Exosomes Research: A Global Visualized Analysis
Bin Wang1, Dan Xing2, Yuanyuan Zhu3
1Orthopedic Department, Second Hospital of Shanxi Medical University, Taiyuan, China.
Biomed Research International
|May 11, 2019
Summary
Global exosomes research is rapidly expanding, with the USA leading in publications and citations. Future efforts should focus on mechanism studies, identified as a key area for future exosome research.
Area of Science:
- Biomedical Sciences
- Molecular Biology
- Cell Biology
Background:
- Exosomes are extracellular vesicles involved in intercellular communication.
- Research into exosomes has seen significant global growth.
- Understanding the trends and status of exosome research is crucial.
Purpose of the Study:
- To investigate the global status and research trends in the field of exosomes.
- To identify key contributors and emerging areas in exosome research.
Main Methods:
- Bibliometric analysis of publications from 1994 to 2017 from the Web of Science database.
- Utilized VOS viewer software for bibliographic coupling, coauthorship, cocitation, and cooccurrence analyses.
- Analyzed publication trends and research clusters.
Main Results:
- A total of 4960 publications were analyzed, showing a consistent annual increase in research output.
- The USA dominated global research contributions, citations, and H-index.
- PLOS ONE was the most prolific journal, and the Natl Canc Ctr the leading institution.
- Research clusters identified include mechanism, in vivo, and in vitro studies.
Conclusions:
- Exosome research is a growing global field with increasing publication rates.
- Mechanism studies are predicted to be a future focus and a hot spot in exosome research.
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