Related Experiment Video
Updated: Jan 25, 2026

Isolation and Characterization of RNA-Containing Exosomes
Published on: January 9, 2012
The State of Exosomes Research: A Global Visualized Analysis
Bin Wang1, Dan Xing2, Yuanyuan Zhu3
1Orthopedic Department, Second Hospital of Shanxi Medical University, Taiyuan, China.
Objective:
With the development of exosomes studies increased around the whole world. Our present study was aimed to investigate the global status and trends in exosomes field.
Methods:
Publications related to exosomes studies from 1994 to 2017 were retrieved from the Web of Science database. The data source was studied and indexed by using bibliometric methodology. For visualized study, VOS viewer software was used to conduct bibliographic coupling analysis, coauthorship analysis, cocitation analysis, and cooccurrence analysis and to analyze the publication trend in exosomes research.
Results:
A total of 4960 publications were included. The relative research interests and number of publications were increasing per year globally. The USA made the highest contributions to the global research with the most citations, the highest H-index, and the most total link strength, while Sweden had the highest average citation per item. The journal PLOS ONE had the highest publication number. The Natl Canc Ctr was the most contributive institutions. Studies could be divided into three clusters: mechanism study, in vivo study, and in vitro study.
Conclusions:
The efforts should be put into mechanism studies, predicted to be the next hot spots in exosomes studies.
Related Concept Videos
Global Climate Change
Overview of Exosomes
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
Introduction to Global Positioning System
Global Regulatory Systems
Errors in Global Positioning System
Field Application of Global Positioning System

