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Dermal elastolysis in the setting of combination immunotherapy
Kirsten E Dickinson1, Lulit Price1,2, Karolyn A Wanat1,3,2,4,5
1Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, IA.
Abstract:
Multiple cutaneous side effects have been reported with the use of immunotherapies including programmed cell death protein 1 inhibitors. We report 2 patients who presented with papillary dermal elastolysis presenting as multiple, skin-colored, wrinkled papules and atrophic macules following an inflammatory eruption in the setting of combination chemotherapy with nivolumab and cabiralizumab. These two cases highlight a novel finding, elastolysis in the setting of chemotherapy with nivolumab and cabiralizumab.
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