Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Movement of Organelles and Vesicles01:43

The Movement of Organelles and Vesicles

6.2K
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
6.2K
Tooth Anatomy01:21

Tooth Anatomy

2.1K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.1K
Anatomical Movements00:51

Anatomical Movements

15.5K
Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
15.5K
The Extracellular Matrix01:42

The Extracellular Matrix

88.4K
Overview
88.4K
The Extracellular Matrix01:29

The Extracellular Matrix

12.0K
Overview
In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
Composition of the Extracellular Matrix
The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...
12.0K
Movement Joints in Buildings01:27

Movement Joints in Buildings

340
Movement joints in buildings are essential design elements that accommodate inevitable motions caused by various factors such as temperature changes, moisture content variations, and structural deflections. These motions, if not considered in design and construction, can lead to unsightly or dangerous damage. Movement joints are incorporated in different forms to manage these stresses and allow materials to move without causing distress.
The simplest type of movement joints, working joints, are...
340

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced Pro-Osteogenic Regulatory Modulation in Mesenchymal Stem Cells Derived from the Periosteum Under Simulated Microgravity.

Cells·2026
Same author

Hypoxia-Inducible Factors in Rheumatoid Arthritis: Central Pathogenic Roles and Therapeutic Opportunities.

Journal of inflammation research·2026
Same author

The dual molecular identity of vestibular kinocilia bridges structural and functional traits of primary and motile cilia.

eLife·2026
Same author

Structuring PVC circularity in the built environment: A systems-based ISM-MICMAC analysis.

Journal of environmental management·2026
Same author

Recoverable fault behavior oriented diagnostic-prognostic hybrid framework for proton exchange membrane fuel cells.

ISA transactions·2026
Same author

Molecular Modeling and Dynamics of a Complete Connexin-43 Gap Junction Channel in Various Phosphorylation States.

The journal of physical chemistry. B·2026

Related Experiment Video

Updated: Jan 25, 2026

Author Spotlight: Peptidome Extraction from Small Extracellular Vesicles Isolated from Bone Marrow-Derived Macrophages
08:34

Author Spotlight: Peptidome Extraction from Small Extracellular Vesicles Isolated from Bone Marrow-Derived Macrophages

Published on: June 30, 2023

2.5K

Extracellular vesicle identification in tooth movement models.

L Shannon Holliday1,2, Estella Truzman1, Jian Zuo1

  • 1Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Florida.

Orthodontics & Craniofacial Research
|May 11, 2019
PubMed
Summary
This summary is machine-generated.

Extracellular vesicles (EVs) are key to cell communication and bone remodeling during orthodontic tooth movement (OTM). Studying EVs in gingival crevicular fluid (GCF) may reveal biomarkers for enhanced OTM and dental pathologies.

Keywords:
biomarkerexosomemicrovesicleorthodonticstooth

More Related Videos

Studying Orthodontic Tooth Movement in Mice
07:17

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

1.5K
Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
07:32

Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment

Published on: February 23, 2024

1.8K

Related Experiment Videos

Last Updated: Jan 25, 2026

Author Spotlight: Peptidome Extraction from Small Extracellular Vesicles Isolated from Bone Marrow-Derived Macrophages
08:34

Author Spotlight: Peptidome Extraction from Small Extracellular Vesicles Isolated from Bone Marrow-Derived Macrophages

Published on: June 30, 2023

2.5K
Studying Orthodontic Tooth Movement in Mice
07:17

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

1.5K
Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
07:32

Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment

Published on: February 23, 2024

1.8K

Area of Science:

  • Biomedical Engineering
  • Cell Biology
  • Orthodontics

Background:

  • Extracellular vesicles (EVs), including exosomes and microvesicles, are critical for intercellular communication.
  • EVs play a role in regulating bone remodeling processes, which are fundamental to orthodontic tooth movement (OTM).
  • Gingival crevicular fluid (GCF) is a potential source of EVs relevant to OTM.

Purpose of the Study:

  • To review available and emerging methods for detecting and studying EVs in the context of OTM.
  • To explore the potential of EVs in GCF as biomarkers for OTM, bone remodeling, and root resorption.
  • To identify how understanding EV function can lead to improved OTM procedures.

Main Methods:

  • Review of current and emerging techniques for EV detection and characterization, such as electron microscopy, nanoparticle tracking, ExoView, and micro-/nanofluidics.
  • Analysis of EV detection in gingival crevicular fluid (GCF).
  • Consideration of techniques like polymerase chain reaction (PCR) for signal amplification.

Main Results:

  • EVs are present in GCF and may be released by osteoclasts during resorption.
  • Emerging technologies show promise for analyzing EVs in GCF.
  • EVs in GCF could serve as biomarkers for bone remodeling, root resorption, and other dental conditions during OTM.

Conclusions:

  • EVs are implicated in the regulation of bone remodeling during OTM.
  • GCF is a valuable source for studying EVs related to OTM.
  • Further research into EVs and their detection methods can enhance orthodontic treatments and diagnostics.