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Disseminated Salmonella infection

Muhamad Izzad Johari1, Alwi Muhd Besari2, Wan Syamimee Wan Ghazali1

  • 1Internal Medicine, University Sains Malaysia-Health Campus, Kubang Kerian, Kelantan, Malaysia.

BMJ Case Reports
|May 12, 2019
PubMed

Insights

Disseminated Salmonella infection led to severe pericardial and pleural empyema in a patient. Prompt antibiotic treatment and fluid drainage resulted in a full recovery.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Pulmonology

Background:

  • Disseminated Salmonella infections are rare but can lead to severe complications.
  • Empyema, a collection of pus in the pleural space, can arise from various infections.
  • Pericardial effusion, fluid around the heart, can also be a consequence of systemic infections.

Observation:

  • A 47-year-old man presented with prolonged fever, poor oral intake, and weight loss.
  • Clinical evaluation revealed disseminated Salmonella infection.
  • The infection complicated into both pericardial and pleural empyema.

Findings:

  • Cultures of pericardial and pleural fluids confirmed Salmonella species.
  • Serial blood cultures were negative for Salmonella.
  • Contrast-enhanced CT of the thorax demonstrated significant pleural and pericardial effusions.

Implications:

  • This case highlights the potential for Salmonella to cause severe, localized infections in serous cavities.
  • Early diagnosis and combined medical and surgical management are crucial for favorable outcomes.
  • Further research into the mechanisms of Salmonella dissemination and localization is warranted.
Keywords:
pericardial diseasetropical medicine (infectious disease)

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