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Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications
Published on: June 23, 2016
ThThnated Development of a pH assisted AgNP-based colorimetric sensor Array for simultaneous identification of
A Orouji1, S Abbasi-Moayed1, M Reza Hormozi-Nezhad2
1Chemistry Department, Sharif University of Technology, Tehran 11155-9516, Iran.
Abstract:
Development of simple and rapid methods for identification of pesticides, due to their broad usage and harmful effects on mammals, has been known as a critical demand. Herein, we have introduced a silver nanoparticle (AgNP) based colorimetric sensor array for simultaneous identification of Azinphosmethyl (AM) and Phosalone (PS) pesticides. In the presence of the target pesticides, unmodified AgNPs at various pHs (4.5, 5.5 and 9.5) showed different aggregation behaviors. As a result of aggregation, the color and UV-Vis spectra of AgNPs changed differentially, leading to distinct response patterns for AM and PS. The aggregation induced spectral changes of AgNPs, were used to identify AM and PS with the help of linear discriminant analysis (LDA). The applicability of the proposed sensor array was then evaluated by identifying the target pesticides in apple samples. Altogether, the developed AgNPs based colorimetric sensor array can be potentially exploited as an efficient discrimination tool in the near future for agrichemical applications.
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