DSA--control of implanted devices for arterial hepatic perfusion

Area of Science:

• Interventional Radiology
• Oncology
• Vascular Imaging

Background:

• Hepatic arterial chemotherapy delivery requires precise visualization for optimal treatment.
• Conventional film angiography has limitations in assessing perfusion patterns.
• Implanted Infusaid or Port-A devices necessitate reliable methods for monitoring chemotherapy delivery.

Purpose of the Study:

• To evaluate the efficacy of digital subtraction angiography (DSA) in visualizing hepatic arterial chemotherapy perfusion.
• To compare DSA's accuracy with nuclide scintigraphy in detecting perfusion defects.
• To assess DSA's sensitivity in identifying aberrant extrahepatic perfusion and vascular complications.

Main Methods:

• DSA was performed in 40 patients with implanted Infusaid or Port-A devices receiving hepatic arterial chemotherapy.
• Perfusion patterns were analyzed, comparing DSA findings with nuclide scintigraphy.
• The study specifically examined cases with nonligated right hepatic arteries and evaluated vascular lesions.

Main Results:

• DSA consistently visualized the perfusion pattern of hepatic arterial chemotherapy.
• DSA accurately identified incomplete perfusion of liver regions, comparable to nuclide scintigraphy.
• DSA demonstrated higher sensitivity in detecting aberrantly perfused extrahepatic regions, particularly with nonligated right hepatic arteries.
• DSA provided satisfactory analysis of specific vascular lesions and complicating events.

Conclusions:

• DSA is a reliable and accurate method for visualizing hepatic arterial chemotherapy perfusion in patients with implanted Infusaid or Port-A devices.
• DSA offers superior sensitivity for detecting aberrant extrahepatic perfusion compared to nuclide scintigraphy.
• DSA is crucial for the comprehensive analysis of vascular details and complications in hepatic arterial chemotherapy delivery.