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Atypical Wounds; Hyperbaric Oxygen Therapy.

Carol Deane Benedict Mitnick1, Kelly Johnson-Arbor2

  • 1Division of Rheumatology, Immunology and Allergy, Center for Wound Healing, MedStar Georgetown University Hospital, 3800 Reservoir Road Northwest, 3PHC, Suite 3004, Washington, DC 20007, USA.

Clinics in Podiatric Medicine and Surgery
|May 14, 2019
PubMed
Summary
This summary is machine-generated.

Severe diabetic foot ulcers unresponsive to conventional treatment may benefit from hyperbaric oxygen therapy. Evaluation for atypical causes and referral to wound healing centers are crucial for effective limb salvage.

Keywords:
Atypical ulcersAutoimmune disordersCoagulopathyDiabetesHyperbaric oxygenationPeripheral vascular diseaseVasculitisWound healing

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Area of Science:

  • Diabetic Foot Ulcer Management
  • Hyperbaric Medicine
  • Wound Healing Research

Background:

  • Severe diabetic foot ulcerations often resist standard therapies.
  • Atypical wound etiologies require specific diagnostic approaches.
  • Hyperbaric oxygen therapy (HBOT) is an alternative for refractory cases.

Purpose of the Study:

  • To evaluate the role of hyperbaric oxygen therapy in severe diabetic foot ulcers.
  • To highlight the importance of assessing atypical wound causes.
  • To emphasize comprehensive medical evaluation for wound healing.

Main Methods:

  • Medical evaluation including history, physical exam, lab tests, and biopsy.
  • Administration of hyperbaric oxygen therapy at 2-3 atmospheres absolute (ATA) with 100% oxygen.
  • Referral to multidisciplinary wound healing centers for complex cases.

Main Results:

  • Hyperbaric oxygen therapy promotes wound neovascularization.
  • Enhanced limb salvage rates are observed with HBOT.
  • Systematic evaluation aids in identifying non-healing ulcer etiologies.

Conclusions:

  • Hyperbaric oxygen therapy is a viable option for severe diabetic foot ulcers failing conventional treatment.
  • Thorough patient evaluation, including for atypical causes, is essential.
  • Multidisciplinary care improves outcomes in complex wound healing.