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Published on: June 10, 2025
Glucose Metabolism Abnormalities in Heart Failure Patients: Insights and Prognostic Relevance
Fabio Marsico1, Paola Gargiulo2, Alberto M Marra2
1Department of Advanced Biomedical Sciences, Federico II University, Via Pansini 5, Naples 80131, Italy; Center for Congenital Heart Disease, University Hospital Inselspital, University of Bern, Switzerland.
Abstract:
Heart failure is a clinical syndrome characterized by left ventricular dysfunction and/or elevated intracardiac pressures, with a prevalence of about 1% to 2% in the general population. In the last decades, many metabolic disorders have been studied as linked with heart failure. Diabetes mellitus and insulin resistance are strictly related to heart failure, with a bidirectional link, where each can influence the other. The aim of this article is to report the role of glucose metabolism abnormalities in the development of heart failure, defining the epidemiology and assessing pathophysiology and prognosis of heart failure related to glucose metabolism disorders.
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