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Related Concept Videos

Hybrid Zones02:29

Hybrid Zones

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Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.
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Hybridization of Atomic Orbitals I03:24

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The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
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Hybridization of Atomic Orbitals II03:35

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sp3d and sp3d 2 Hybridization
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In-situ Hybridization02:31

In-situ Hybridization

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
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IR Absorption Frequency: Hybridization01:21

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Hydrocarbons such as alkanes, alkenes, and alkynes show characteristic C–H stretching absorption bands. These IR stretching frequencies depend on the hybridization of the involved carbon atom and can be explained in terms of the s character of each hybridized atomic orbital.
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Resonance and Hybrid Structures02:16

Resonance and Hybrid Structures

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According to the theory of resonance, if two or more Lewis structures with the same arrangement of atoms can be written for a molecule, ion, or radical, the actual distribution of electrons is an average of that shown by the various Lewis structures.
Resonance Structures and Resonance Hybrids
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N–O and N=O bonds.
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Related Experiment Video

Updated: Jan 25, 2026

Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy
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Hybrid esophagectomy.

Thibault Voron1,2, Alexandru Lintis1,3,4, Guillaume Piessen1,3,4

  • 1Department of Digestive and Oncological Surgery, Claude Huriez University Hospital, Lille, France.

Journal of Thoracic Disease
|May 14, 2019
PubMed
Summary
This summary is machine-generated.

The hybrid esophagectomy approach offers improved postoperative outcomes and survival rates compared to open surgery for esophageal cancer. It demonstrates comparable results to totally minimally invasive esophagectomy, particularly for pulmonary complications.

Keywords:
Esophaguscancer surgeryhybridlaparoscopyminimally invasivereviewthoracoscopy

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Area of Science:

  • Surgical Oncology
  • Thoracic Surgery
  • Minimally Invasive Surgery

Background:

  • Esophagectomy for cancer carries significant mortality and morbidity, primarily pulmonary complications.
  • Minimally invasive techniques, including totally minimally invasive esophagectomy (MIE) and hybrid esophagectomy, aim to reduce postoperative morbidity.

Purpose of the Study:

  • To review the outcomes of the hybrid esophagectomy approach for esophageal cancer.
  • To compare hybrid esophagectomy with open and totally MIE approaches.

Main Methods:

  • Review of existing literature on hybrid esophagectomy for esophageal cancer.
  • Comparison of postoperative and long-term outcomes between hybrid, open, and totally MIE esophagectomy.

Main Results:

  • Hybrid esophagectomy shows better postoperative outcomes than open esophagectomy.
  • Pulmonary complication rates are similar between hybrid esophagectomy and totally MIE.
  • Long-term survival with hybrid esophagectomy is comparable or better than with open esophagectomy.

Conclusions:

  • Hybrid esophagectomy presents a promising approach with favorable outcomes and a short learning curve.
  • Hybrid esophagectomy with laparoscopic gastric mobilization may become the future standard of care.
  • Further comparative studies between hybrid and totally MIE are warranted.