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Updated: Jan 25, 2026

Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope
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Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope

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Sticks and bones: Traumatic phaeohyphomycosis presenting as an epidural scalp abscess and cranial osteomyelitis

Richard L Oehler1,2, Ju Hee Katzman2, Natan Kraitman2

  • 1James A Haley Veterans Hospital, 13,000 Bruce B Downs Blvd, #111J, Tampa, FL 33612, USA.

Medical Mycology Case Reports
|May 14, 2019
PubMed

Insights

Pigmented molds can cause phaeohyphomycosis, a serious infection. A 76-year-old man developed a scalp abscess and bone infection from Cladophialophora bantiana after tree branch exposure, requiring surgery and antifungal treatment.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Pigmented molds, such as Cladophialophora species, are known etiological agents of phaeohyphomycosis.
  • Phaeohyphomycosis can manifest as superficial, subcutaneous, or deeply invasive disease, even in immunocompetent individuals.

Observation:

  • A case of a 76-year-old male patient is presented.
  • The patient developed a posterior scalp abscess and cranial osteomyelitis.
  • This condition arose subsequent to an incidental scalp injury from a tree branch.

Findings:

  • The causative agent was identified as Cladophialophora bantiana.
  • The infection involved both soft tissue (abscess) and bone (osteomyelitis) of the scalp and cranium.
  • Successful management involved extensive surgical debridement and a prolonged course of antifungal therapy.

Implications:

  • This case highlights the potential for Cladophialophora bantiana to cause severe invasive infections in immunocompetent hosts.
  • Prompt diagnosis and aggressive management, including surgical intervention and systemic antifungals, are crucial for favorable outcomes.
  • Awareness of environmental fungal exposures is important for preventing such infections.
Keywords:
Cladophialophora bantiatumCladosporiumCranialOsteomyelitisPhaeohyphomycosis

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