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Ethnic Differences in 90-Day Poststroke Medication Adherence.

Rebecca J Lank1, Lynda D Lisabeth1,2, Deborah A Levine1,3

  • 1From the Stroke Program (R.J.L., L.D.L., D.A.L., D.B.Z., K.A.K., B.G.Z., G.M.C., D.L.B., L.B.M.), University of Michigan, Ann Arbor.

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Summary
This summary is machine-generated.

This study found no ethnic differences in medication adherence 3 months after ischemic stroke between Mexican Americans and non-Hispanic whites. This suggests other factors, not patient-level adherence, may explain stroke recurrence disparities.

Keywords:
Mexican Americansanticoagulantsdiabetes mellitushypertensionmedication adherence

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Area of Science:

  • Neurology
  • Public Health
  • Health Disparities

Background:

  • Stroke recurrence risk is higher in Mexican Americans compared to non-Hispanic whites.
  • Investigating medication adherence is crucial for understanding stroke recurrence disparities.

Purpose of the Study:

  • To assess ethnic differences in medication adherence 3 months post-stroke.
  • To explore medication adherence as a potential factor in stroke recurrence disparities between Mexican Americans and non-Hispanic whites.

Main Methods:

  • A population-based study of ischemic stroke cases from 2008-2015.
  • Prospective follow-up for 3 months to assess adherence to 5 drug classes: statins, antiplatelets, anticoagulants, antihypertensives, and antidepressants.
  • Statistical analysis using chi-squared or Kruskal-Wallis tests and multivariable logistic regression.

Main Results:

  • Mexican Americans were younger and had higher rates of diabetes and hypertension but lower rates of atrial fibrillation and smoking compared to non-Hispanic whites.
  • No significant ethnic differences were observed in medication adherence across the 5 analyzed drug classes.
  • Key demographic and clinical factors did not significantly differ by ethnicity.

Conclusions:

  • Medication adherence does not appear to explain the observed disparities in stroke recurrence between Mexican Americans and non-Hispanic whites.
  • Further research should explore provider and health system factors contributing to stroke recurrence burden in Mexican Americans.