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During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
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Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
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Postinfarction Ventricular Septal Defect Closure

Norihiko Kamioka1, Robert J Lederman2, Adam B Greenbaum1

  • 1Division of Cardiology (N.K., A.B.G., A.Y., P.T.G., P.C.B., V.C.B.), Emory University School of Medicine, Atlanta, GA.

Circulation. Cardiovascular Interventions
|May 16, 2019
PubMed
Summary

No abstract available in PubMed .

Keywords:
BASSINETCribriformhybrid closurepost-infarctventricular septum defect

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