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Updated: Jan 24, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
[Neuropathology of Neuropsychiatric Systemic Lupus Erythematosus (NPSLE)]
1Department of Neurology, Saitama International Medical Center.
Abstract:
Neuropathologic alterations of neuropsychiatric systemic lupus erythematosus (NPSLE) are characterized by small vessel changes such as endothelial proliferation, fibrosis, hyalinization, fibrinoid necrosis, and thrombus formation. Pathologic ischemic and hemorrhagic changes. In some instances, vasculitis and perivascular infiltration of inflammatory cells are seen. In the spinal cord, degenerative changes of entire margin of the spinal cord may also be present.
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