Which one predicts mortality better? Hemogram and ST elevation myocardial infarction.

Area of Science:

• Cardiology
• Hematology
• Emergency Medicine

Background:

• Predicting in-hospital mortality in ST-elevation myocardial infarction (STEMI) is crucial for timely intervention.
• Hematological parameters offer a potentially accessible and rapid method for risk stratification.

Purpose of the Study:

• To evaluate the predictive power of admission hematological parameters for in-hospital mortality in STEMI patients.
• To identify specific cut-off values for these parameters.

Main Methods:

• A cohort of 1,929 adult STEMI patients was analyzed.
• Admission levels of white blood cells (WBC), red cell distribution width, mean platelet volume, and neutrophil-to-lymphocyte ratio (NLR) were recorded.
• Cardiac markers (CK-MB, Troponin T) were also assessed.

Main Results:

• The study included 71.7% males and 28.3% females, with a 7.5% in-hospital mortality rate.
• Receiver operating characteristic (ROC) analysis identified NLR as the strongest predictor of mortality (AUC=0.772).
• White blood cell (WBC) count was the second strongest predictor (AUC=0.749).

Conclusions:

• Admission WBC and particularly NLR values are powerful and easily obtainable predictors of mortality in STEMI.
• These hematological markers can aid in the rapid implementation of treatment strategies for STEMI patients.