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Effects of OSA Surgery on Ophthalmological Microstructures
Pei-Wen Lin1, Hsin-Ching Lin2,3,4, Michael Friedman5,6
11 Department of Ophthalmology, Division of Glaucoma, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
The Annals of Otology, Rhinology, and Laryngology
|May 17, 2019
Summary
Upper airway surgery improved visual function and retinal thickness in patients with severe obstructive sleep apnea (OSA). This study shows potential benefits of surgery for ocular health in OSA patients.
Area of Science:
- Ophthalmology and Sleep Medicine
- Investigates the intersection of ocular health and sleep-disordered breathing.
Background:
- Obstructive sleep apnea/hypopnea syndrome (OSA) may negatively impact optic nerve oxygenation, potentially leading to glaucomatous optic neuropathy.
- Limited research exists on visual function and retinal microstructure changes post-upper airway surgery in OSA patients.
Purpose of the Study:
- To evaluate changes in visual sensitivity and retinal fiber layer thickness in OSA patients before and after upper airway surgery.
- To assess the impact of surgical intervention on ocular parameters in individuals with OSA.
Main Methods:
- Prospective, single-blind study involving 108 OSA patients undergoing upper airway surgery after failed conservative therapy.
- Comprehensive ophthalmologic evaluations, including standard automated perimetry (SAP) and spectral-domain optical coherence tomography (OCT), were performed at baseline and 6 months post-surgery.
- Polysomnographic (PSG) findings were recorded pre- and postoperatively.
Main Results:
- Six months after surgery, significant improvements were observed in major PSG parameters, mean deviation, and pattern standard deviation on SAP.
- In the severe OSA group (apnea/hypopnea index ≥30/hour), OCT measurements revealed a significant increase in macular layer (ML) thickness across multiple sectors and total ML thickness post-surgery.
Conclusions:
- Upper airway surgery led to significant improvements in visual sensitivities (SAP), macular layer thickness (OCT), and oxygenation status (PSG) in severe OSA patients.
- Surgical intervention for upper airway obstruction appears to positively impact retinal microstructures in patients with severe OSA.
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