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Related Experiment Videos

Inner-city survey for tuberculosis: evaluation of diagnostic methods.

S Grzybowski, E A Allen, W A Black

    The American Review of Respiratory Disease
    |June 1, 1987
    PubMed
    Summary

    Active tuberculosis case-finding in Vancouver identified 8 new cases. Chest x-rays and sputum tests were effective, highlighting the value of targeted screening in high-incidence urban populations.

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    Risk factors for unfavourable treatment outcome among new smear-positive pulmonary tuberculosis cases in China.

    Public health action·2018

    Area of Science:

    • Public Health and Epidemiology
    • Infectious Disease Control
    • Respiratory Medicine

    Background:

    • Socially and economically depressed inner-city areas often harbor higher tuberculosis (TB) prevalence.
    • Effective case-finding strategies are crucial for controlling TB transmission in vulnerable populations.
    • Evaluating diagnostic methods' utility in real-world screening campaigns is essential.

    Purpose of the Study:

    • To assess the acceptance and yield of a tuberculosis case-finding campaign in an inner-city Vancouver population.
    • To compare the effectiveness of chest x-ray, sputum smear, and tuberculin skin testing in detecting active pulmonary tuberculosis.
    • To determine the prevalence of tuberculosis in this specific high-risk demographic.

    Main Methods:

    • A voluntary tuberculosis case-finding campaign was conducted, offering chest x-ray, on-the-spot sputum collection, and tuberculin skin testing.

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  • Diagnostic data from 1,271 participants were analyzed.
  • Sputum specimens were examined via smear and culture; chest x-rays were reviewed; tuberculin skin tests were administered.

    • Main Results:

    • High participant acceptance was observed for all offered diagnostic methods.
    • Eight cases of bacteriologically confirmed pulmonary tuberculosis were identified.
    • Examination of two sputum specimens successfully diagnosed all identified active TB cases.

    Conclusions:

    • Chest radiography or examination of two sputum specimens demonstrated comparable effectiveness in detecting active pulmonary tuberculosis in this setting.
    • Sputum smear examination rapidly identified infectious TB cases.
    • The high prevalence rate (629/100,000) underscores the effectiveness of active case-finding in high-incidence urban populations.