Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

48.3K
Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
48.3K
Sperm Transport01:15

Sperm Transport

3.3K
The journey of sperm from its origin to the point of ejaculation begins within the seminiferous tubules of the testis. Here, Sertoli cells produce fluid that propels non-motile sperm through a series of conduits, starting with the straight tubules leading to the rete testis. This interconnected network of tubules acts as the initial pathway for sperm, guiding them into the efferent ductules and then into the epididymis for maturation.
The maturation phase occurs in the epididymis, where sperm...
3.3K
Planar Rigid-Body Motion01:22

Planar Rigid-Body Motion

1.0K
Understanding the movement of a rigid body in planar motion involves recognizing that every particle within this body is traversing a path that maintains a consistent distance from a specific plane. This concept is fundamental in the study of physics and mechanical engineering, and it allows us to comprehend better how objects move in space.
Planar motion is typically divided into three distinct categories. The first is rectilinear translation, demonstrated by a subway train that moves along...
1.0K
Gauss's Law: Planar Symmetry01:27

Gauss's Law: Planar Symmetry

9.4K
A planar symmetry of charge density is obtained when charges are uniformly spread over a large flat surface. In planar symmetry, all points in a plane parallel to the plane of charge are identical with respect to the charges. Suppose the plane of the charge distribution is the xy-plane, and the electric field at a space point P with coordinates (x, y, z) is to be determined. Since the charge density is the same at all (x, y) - coordinates in the z = 0 plane, by symmetry, the electric field at P...
9.4K
What is Natural Selection?01:32

What is Natural Selection?

126.4K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
126.4K
Sperm Structure and Semen Composition01:22

Sperm Structure and Semen Composition

10.8K
During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
10.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High seminal BPA in IVF patients correlates with lower sperm count and up-regulated miR-21 and miR-130a.

Reproductive toxicology (Elmsford, N.Y.)·2024
Same author

Solid-state Fluorescence from Carbon Dots Widely Tunable from Blue to Deep Red through Surface Ligand Modulation.

Angewandte Chemie (International ed. in English)·2022
Same author

Silver nanoparticles modified hFGF2-linking camelina oil bodies accelerate infected wound healing.

Colloids and surfaces. B, Biointerfaces·2022
Same author

Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands.

National science review·2022
Same author

Sulfur-Doped Carbon for Potassium-Ion Battery Anode: Insight into the Doping and Potassium Storage Mechanism of Sulfur.

ACS nano·2022
Same author

Metabolomics study identified bile acids as potential biomarkers for gastric cancer: A case control study.

Frontiers in endocrinology·2022

Related Experiment Video

Updated: Jan 24, 2026

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index
09:16

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index

Published on: March 28, 2025

628

Two-dimensional planar swimming selects for high DNA integrity sperm.

Jason Riordon1, Farhang Tarlan, Jae Bem You

  • 1Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Rd, Toronto, Ontario M5S 3G8, Canada. sinton@mie.utoronto.ca.

Lab on a Chip
|May 17, 2019
PubMed
Summary

This study introduces a novel sperm selection method using confined channels. This technique isolates sperm with superior DNA integrity, outperforming current clinical methods for improved assisted reproductive technology outcomes.

More Related Videos

Planar and Three-Dimensional Printing of Conductive Inks
10:49

Planar and Three-Dimensional Printing of Conductive Inks

Published on: December 9, 2011

37.8K
Fluorimetric Techniques for the Assessment of Sperm Membranes
08:58

Fluorimetric Techniques for the Assessment of Sperm Membranes

Published on: November 28, 2018

14.2K

Related Experiment Videos

Last Updated: Jan 24, 2026

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index
09:16

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index

Published on: March 28, 2025

628
Planar and Three-Dimensional Printing of Conductive Inks
10:49

Planar and Three-Dimensional Printing of Conductive Inks

Published on: December 9, 2011

37.8K
Fluorimetric Techniques for the Assessment of Sperm Membranes
08:58

Fluorimetric Techniques for the Assessment of Sperm Membranes

Published on: November 28, 2018

14.2K

Area of Science:

  • Reproductive Biology
  • Sperm Selection Technologies
  • Assisted Reproductive Technologies (ART)

Background:

  • High-quality sperm selection is crucial for successful assisted reproductive technologies (ART).
  • Current clinical sperm screening methods primarily rely on motility assessments under free or boundary-following conditions.
  • Limitations exist in current methods for effectively isolating sperm with optimal DNA integrity.

Purpose of the Study:

  • To develop and evaluate a novel sperm selection approach utilizing confined microchannels.
  • To assess the DNA integrity of sperm selected via a planar swimming mechanism.
  • To compare the efficacy of this new method against existing clinical sperm selection techniques.

Main Methods:

  • A sperm selection method employing parallel 2 μm tall confined channels was developed.
  • These channels restrict sperm head rotation, enforcing planar swimming.
  • DNA integrity of selected sperm was assessed and compared to raw and conventionally selected sperm populations.

Main Results:

  • Sperm selected via planar swimming within confined channels exhibited significantly higher DNA integrity.
  • This improvement was observed across various semen sample qualities, including donor and clinical patient samples.
  • The planar swimming selection method demonstrated superior performance compared to density gradient centrifugation, swim-up, and general motility selection.

Conclusions:

  • Planar swimming in confined channels is a viable mechanism for selecting sperm with enhanced DNA integrity.
  • This novel approach holds potential for improving outcomes in assisted reproductive technologies for individuals and offspring.
  • The method offers a promising alternative to current clinical sperm selection strategies.