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A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Home parenteral nutrition in pediatric patients with intestinal insufficiency
Yazmín Zapata Olivares1, María Isabel Hodgson Bunster1, María Luisa Cordero Bayón2
1Departamento de Nutrición, Diabetes y Metabolismo, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Insights
The study identified 46 pediatric patients receiving home parenteral nutrition (HPN) for intestinal insufficiency in Chile. No significant differences were found in outcomes between home and hospital settings, supporting home-based HPN.
Area of Science:
- Pediatric Gastroenterology
- Clinical Nutrition
- Public Health Policy
Background:
- Home parenteral nutrition (HPN) offers benefits but its prevalence in Chile is unknown.
- Intestinal insufficiency (II) necessitates long-term nutritional support.
- Understanding the patient population is crucial for healthcare planning.
Purpose of the Study:
- Determine the prevalence of patients receiving HPN in Chile.
- Characterize the clinical profile of these patients.
- Evaluate factors influencing treatment setting (home vs. hospital).
Main Methods:
- Cross-sectional descriptive study of 46 pediatric patients (0-18 years) with II.
- Data collected via digital survey on demographics, PN history, CVC type, and complications.
- Statistical analysis using SPSS, including frequency, central trend, Chi-square, and Fisher tests.
Main Results:
- Prevalence data for 46 patients with a mean age of 55.5 months.
- Primary indication for PN was decreased intestinal surface (78.3%).
- 63% of patients were hospitalized; no significant differences in nutritional status or catheter infections between home and hospital settings.
Conclusions:
- Prevalence and clinical characteristics of long-term PN patients were identified.
- No evidence supports hospital administration over home-based HPN.
- Public policies are needed to ensure access to home HPN.
Introduction:
Home parenteral nutrition (HPN) has been shown to offer important benefits for pa tients and the health system. In Chile, the number of patients who are receiving this type of treatment or who could be candidates for it is unknown. Objetive: To determine the prevalence and clinical characteristics of patients with intestinal insufficiency (II) currently receiving HPN or who are can didates for it.
Patients And Method:
Cross-sectional descriptive study which included patients aged between 0 to 18 years with diagnosis of II who were receiving parenteral nutrition (PN) for over three months, either at home or in the hospital, with a stable clinical situation and a long-term venous catheter (CVC). Through a digitalized survey, the following variables were collected and studied: gender, birth history, indication to initiate parenteral nutritional support, age of initiation of PN, type of CVC, frequency of PN, nutritional status and feeding in the last control and complications as sociated with the use of PN. Data analysis was performed using the SPSS Statistics Software, Version 21, Macintosh. The descriptive analysis considered frequency analysis and central trend measures. The Chi-square and Fisher tests were used for comparison of proportions.
Results:
Data from 46 patients were recorded. The average age was 55.5 months. The main indication for initiating the PN was the decrease of the intestinal surface (78.3%). 63% of the patients were hospitalized. No signi ficant differences were found between the place of treatment and the nutritional status and catheter infections variables in the last year.
Conclusions:
The prevalence of patients with long-term PN and their clinical characteristics were identified. No differences were found to support the administration of this treatment in the hospital over the home. Public policies must be developed to guarantee the option of receiving this treatment at home.
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