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Corneo-pterygium total area measurements utilising image analysis method.

Hilmi Mohd Radzi1, Mohd Kamal Khairidzan2, Che Amin Mohd Zulfaezal3

  • 1Department of Optometry and Vision Science, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia (IIUM), Kuantan, Pahang, Malaysia; Department of Ophthalmology, Kulliyyah of Medicine, International Islamic University Malaysia (IIUM), Kuantan, Pahang, Malaysia.

Journal of Optometry
|May 18, 2019
PubMed
Summary

A new image analysis method accurately quantifies corneo-pterygium total area (CPTA), showing a strong association with corneal astigmatism (CA). This reliable technique offers objective pterygium measurement in clinical practice.

Keywords:
Análisis de imagenAstigmatismo de la córneaCorneal AstigmatismCorneal-pterigiónCorneo-pterygiumImage analysisPterigiónPterygiumTotal areaÁrea total

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Corneal Disease

Background:

  • Pterygium is a common ocular condition affecting the cornea.
  • Accurate quantification of pterygium size is crucial for assessing its impact.
  • Existing methods for measuring pterygium may lack objectivity and precision.

Purpose of the Study:

  • To introduce an objective image analysis method for quantifying corneo-pterygium total area (CPTA).
  • To evaluate the reliability and clinical utility of this new CPTA measurement technique.
  • To assess the association between CPTA and corneal astigmatism (CA).

Main Methods:

  • 120 patients with primary pterygium were included.
  • Image analysis software was used to manually mark and measure pterygium area in pixels, converted to a percentage of corneal surface area (CPTA).
  • Intra- and inter-observer reliability was assessed using Intraclass Correlation (ICC).

Main Results:

  • The mean CPTA was 45.26±13.51%.
  • Excellent intra- and inter-observer reliability was achieved (ICC > 0.99).
  • The new method showed a positive association with corneal astigmatism and predicted 37% of its variance, outperforming standard methods (21%).

Conclusions:

  • The image analysis method provides a reliable and practical approach for objective pterygium quantification.
  • This technique accurately measures pterygium size, shape, and its effects on corneal curvature.
  • The method is valuable for clinical assessment and research in ophthalmology.