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Updated: Jan 24, 2026
15:18
Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
Published on: July 30, 2009
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Neuroimaging selection for thrombectomy in pediatric stroke: a single-center experience
Sarah Lee1,2, Jeremy J Heit3, Gregory W Albers1
1Stanford Stroke Center, Department of Neurology & Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Journal of Neurointerventional Surgery
|May 18, 2019
Summary
Pediatric thrombectomy shows promise for acute large vessel occlusion in children, with 78% achieving good outcomes. Further research is needed to establish specific selection criteria for this patient group.
Area of Science:
- Pediatric Neurology
- Interventional Neuroradiology
- Stroke Medicine
Background:
- Delayed diagnosis in children necessitates extended treatment windows for stroke.
- Current selection criteria for pediatric thrombectomy are undefined.
Purpose of the Study:
- To evaluate the safety and efficacy of endovascular therapy in children with acute large vessel occlusion presenting within 24 hours.
- To explore potential outcome predictors in pediatric stroke patients undergoing thrombectomy.
Main Methods:
- Retrospective cohort study of pediatric patients (<18 years) with acute large vessel occlusion within 24 hours.
- Comparison of outcomes between treated and untreated patients using statistical tests.
- Analysis of demographic, clinical, and imaging data.
Main Results:
- Twelve children were included; 75% had cardioembolic stroke.
- Nine patients (75%) were treated with thrombectomy, alone or with IV alteplase.
- Favorable outcomes were achieved in 78% of treated patients versus 0% of untreated patients (P=0.018).
- Older age and outpatient presentation were associated with better outcomes in treated children.
Conclusions:
- Endovascular therapy is feasible and effective in select pediatric stroke patients.
- Perfusion imaging may aid in identifying salvageable tissue, but thresholds may differ from adults.
- Further studies are required to define optimal selection criteria for pediatric thrombectomy.
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