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Updated: Jan 24, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Secondary dengue retinitis with associated occlusive retinal vasculitis
Vikram Vinayak Koundanya1, Neha Chowdhary2, Manisha Agarwal2
1Vitreoretina Services, Dr. Shroff's Charity Eye Hospital, 5027-Kedar Nath Road, Daryaganj, New Delhi, 110002, India. vikramkoundanya@gmail.com.
Secondary dengue infection can cause vision-threatening retinitis. Early diagnosis using the IgG/IgM ratio and prompt treatment with corticosteroids can lead to successful outcomes in dengue retinitis cases.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Immunology
Background:
- Dengue is a prevalent tropical disease.
- Secondary dengue infections can trigger severe immunological responses, including antibody-dependent enhancement (ADE).
- ADE can lead to serious ocular complications such as retinitis.
Purpose of the Study:
- To report a case of secondary dengue retinitis.
- To highlight the clinical presentation and diagnostic methods for dengue retinitis.
- To demonstrate the efficacy of corticosteroid treatment for this condition.
Main Methods:
- Case report of a 42-year-old female patient.
- Diagnostic evaluation included patient history, clinical examination, IgG/IgM ratio assessment, and ELISA for dengue.
- Treatment involved oral corticosteroids.
Main Results:
- The patient was diagnosed with secondary dengue retinitis and retinal vasculitis.
- The diagnosis was confirmed by serological tests and clinical findings.
- Successful treatment was achieved with oral corticosteroids.
Conclusions:
- Secondary dengue infection can present as retinitis with retinal microvascular occlusions.
- A high index of suspicion and utilizing the IgG/IgM ratio are crucial for diagnosing dengue retinitis.
- Corticosteroids are an effective treatment option for secondary dengue retinitis.
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