Related Experiment Video

Updated: Jan 24, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

20.3K

Septic myocardial calcification: A case report

Aniello Maiese1, Federico Manetti2, Raffaele La Russa1

  • 1Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Viale Regina Elena 336, 00161, Italy; IRCCS Neuromed, Via Atinense 18, Pozzilli, 86077, Italy.

Journal of Forensic and Legal Medicine
|May 18, 2019
PubMed

Insights

This study reports a rare case of myocardial calcification in a patient with sepsis. Histological examination revealed extensive calcification in the right atrial wall, highlighting a potential complication of severe sepsis.

Area of Science:

  • Pathology
  • Cardiology
  • Infectious Diseases

Background:

  • Sepsis can lead to various cardiac histological changes, including myocytolysis and fibrosis.
  • Septic myocardial calcification is an exceedingly rare condition with unclear pathogenesis.
  • Existing knowledge on myocardial calcification primarily recognizes metastatic or dystrophic mechanisms.

Observation:

  • A 72-year-old male with polytrauma developed sepsis on day 110.
  • Transesophageal echocardiogram identified right atrial wall calcification; no predisposing systemic factors were noted.
  • The patient died from septic shock and multi-organ failure on day 149.

Findings:

  • Autopsy confirmed a calcified, firm right atrial wall with a greenish-brown formation.
  • Histological examination revealed extensive subendocardial calcification with fibrin deposition and surrounding fibrosis.

Implications:

  • This case expands the understanding of rare cardiac manifestations of severe sepsis.
  • It underscores the importance of considering myocardial calcification in sepsis survivors with cardiac abnormalities.
  • Further research into the specific mechanisms of sepsis-induced myocardial calcification is warranted.

Keywords:
Myocardial calcificationPostmortem diagnosisSepsisSeptic myocardial dysfunction

More Related Videos

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

5.8K
Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals08:02

Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals

Published on: November 15, 2024

988

Related Concept Videos

Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Types of Reports II: Incident or Occurrence Report01:21

Types of Reports II: Incident or Occurrence Report

An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
Types of Reports III: Telephone and Verbal Reports01:26

Types of Reports III: Telephone and Verbal Reports

Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
1000
Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
13.1K
Introduction to Documentation and Reporting01:20

Introduction to Documentation and Reporting

Documentation is the systematic process of formally recording, maintaining, and communicating information.
Nursing documentation records essential information and details regarding a patient's care and treatment in written or electronic form. It is a critical aspect of nursing practice that involves documenting assessments, interventions, outcomes, and other relevant details about a patient's health status.
Documentation maps the patient's health journey by creating a comprehensive...
2.9K