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Published on: November 7, 2020
Cardiac and Neurologic Complications in the Late Period After Liver Transplantation: A Retrospective Analysis of 4
U Dogan1, M Yaprak2, E A Dogan3
1Department of Cardiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Insights
Late cardiac and neurologic complications are common after liver transplantation. A multidisciplinary approach is crucial for managing these diverse post-transplant issues in liver recipients.
Area of Science:
- Transplantation Medicine
- Cardiology
- Neurology
Background:
- Liver transplantation is a life-saving procedure.
- Long-term complications can affect various organ systems.
- Cardiac and neurologic issues require specific attention in post-transplant care.
Purpose of the Study:
- To evaluate the incidence and nature of cardiac and neurologic complications in the late period after liver transplantation.
- To identify prevalent risk factors and symptoms associated with these complications.
Main Methods:
- Retrospective review of medical records of 198 liver transplant recipients.
- Inclusion of patients who received cardiology or neurology consultations during long-term follow-up.
- Analysis of demographic data, pre-existing conditions, and presenting symptoms.
Main Results:
- Thirty patients (30.0%) experienced cardiac or neurologic complications.
- High prevalence of atherosclerotic risk factors including hypertension, diabetes, and hyperlipidemia.
- Common symptoms included chest pain, palpitations, headache, and seizures; stroke and transient ischemic attack were also reported.
Conclusions:
- Liver transplant recipients face a wide spectrum of cardiac and neurologic complications.
- A multidisciplinary approach involving cardiology and neurology is essential for optimal management.
- Early preventive measures and tailored treatment strategies are needed to improve outcomes.
Background And Objective:
The aim of our study was to assess the cardiac and neurologic complications after liver transplantation in the late period.
Method And Patients:
Medical records of 198 patients who had liver transplantation in the organ transplantation center of our university hospital between between February 2014 and October 2017 were reviewed retrospectively. Patients who were consulted by a physician from either the cardiology or neurology departments during their long-term follow-up after liver transplantation were included in the study.
Results:
Thirty patients (9 female; 30.0%) were evaluated by a cardiologist (n = 23; 76.7%) or a neurologist (n = 19; 63.3%) during their long-term-follow-up. The mean age was 55.0 ± 13.3. Atherosclerotic risk factors such as hypertension (n = 10; 33.3%), diabetes mellitus (n = 17; 56.7%), hyperlipidemia (n = 7; 23.3%), and coronary artery disease (n = 7; 23.3%) were highly prevalent. Chest pain (n = 5; 16.7%) was the most encountered symptom. Of these patients, 2 (6.7%) underwent coronary bypass surgery, whereas 1 (3.3%) patient was treated medically. Palpitation was the second most frequent cardiac symptom (n = 3; 10.0%). Atrial fibrillation paroxysm occurred in 2 patients. Headache (n = 4; 13.3%) was the most prevalent neurologic symptom. Transient ischemic attack occurred in 1 patient (3.3%), whereas 2 patients (6.7%) experienced stroke (1 ischemic and the other hemorrhagic). Seizures occurred in 2 patients (6.7%).
Conclusion:
Long-term follow-up of liver transplant recipients might be challenging due to the diversity of symptoms and wide spectrum of cardiac and neurologic complications. A multidisciplinary approach involving cardiologists and neurologists would help to improve early preventive measures and medical treatment strategies.
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