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Updated: Jan 24, 2026

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
Published on: August 26, 2014
Diffuse white matter alteration in CLIPPERS: Advanced MRI findings from two cases
Mauro Morassi1, Milena Cobelli1, Elena Ghiselli1
1Department of Radiology, Neuroradiology and Angiology Unit, Fondazione Poliambulanza Istituto Ospedaliero, Via L. Bissolati 57, 25124 Brescia, Italy.
Advanced MRI revealed widespread white matter changes in patients with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). These findings suggest MRI can help identify CLIPPERS cases potentially progressing to lymphoma.
Area of Science:
- Neuroimaging
- Neurology
- Radiology
Background:
- Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory brain condition.
- Understanding the full extent of white matter involvement in CLIPPERS is crucial for diagnosis and prognosis.
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