Related Experiment Video
Updated: Jan 24, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Comparison of nocturnal pulse oximetry with polysomnography in children with sleep disordered breathing
Catherine Jonas1,2, Surendran Thavagnanam3,4, Gregory Blecher1,2
1Sleep Medicine Department, Sydney Children's Hospital, Randwick, New South Wales, Australia.
Insights
Overnight oximetry is a reliable screening tool for moderate to severe obstructive sleep apnea (OSA) in children. However, a normal or mild score does not exclude OSA, necessitating polysomnography (PSG) for definitive diagnosis.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Diagnostic Accuracy
Background:
- Polysomnography (PSG) is the gold standard for diagnosing obstructive sleep apnea (OSA).
- High costs and limited availability of PSG often lead to diagnostic delays.
- There is a need for reliable, accessible screening tools for pediatric OSA.
Purpose of the Study:
- To evaluate the diagnostic reliability of overnight oximetry as a screening tool for obstructive sleep apnea (OSA) in children.
- To compare the efficacy of the McGill oximetry scoring system against PSG diagnosis.
Main Methods:
- Retrospective study of 110 children suspected of OSA undergoing both overnight oximetry and PSG.
- Comparison of "McGill oximetry scoring" with American Association of Sleep Medicine criteria for OSA diagnosis.
Main Results:
- Overnight oximetry showed an overall sensitivity of 63% and specificity of 78% for OSA diagnosis.
- McGill grades 3 and 4 oximetry scores demonstrated 100% PPV and 78% NPV for moderate/severe OSA.
- Normal or McGill grade 2 oximetry results did not rule out OSA, with 36% and 30% of these patients having mild or moderate/severe OSA, respectively.
Conclusions:
- Overnight oximetry is a valuable tool for screening moderate to severe pediatric OSA.
- A normal or McGill grade 2 oximetry score does not exclude OSA.
- Polysomnography remains essential for definitive OSA diagnosis in children.
Purpose:
Polysomnography (PSG) is the gold standard in the diagnosis of obstructive sleep apnea (OSA). However, due to high cost and limited availability, this is difficult to access and often delayed. To evaluate the reliability of overnight oximetry as a screening tool for OSA diagnosis.
Method:
All children suspected of OSA who underwent an overnight oximetry and subsequent PSG between January 2014 and April 2016 were studied retrospectively. The "McGill oximetry scoring" was compared with OSA diagnosis as per the American Association of Sleep Medicine.
Results:
A total of 110 patients had both oximetry and PSG. Sixty-one children (56%) had normal oximetry, whereas 30 (27%) had McGill grade 2 and 19 (17%) had McGill 3 and 4. Sixty-four percent (64%) of children with normal oximetry had a normal PSG. Seventy percent (70%) of children with McGill 2 had either a normal or mild OSA on PSG. All the children with McGill 3 and 4 had moderate/severe OSA by PSG. The overall sensitivity and specificity of oximetry in identifying OSA were 63% and 78%, respectively, and the positive and negative predictive values (PPV and NPV) were 78% and 64%, respectively. The sensitivity and specificity of McGill 3 and 4 in diagnosing moderate/severe OSA on PSG were 59% and 100%, respectively, and the PPV and NPV were 100% and 78%, respectively.
Conclusion:
Overnight oximetry provides satisfactory diagnostic performance in detecting moderate and severe OSA; however, a normal or McGill 2 score does not rule out OSA and a PSG is required for diagnosis.
Related Concept Videos
Pulse Oximetry
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Breathing
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Pulse
The pulse serves as a clinical...

