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Alternative total synthesis of dendrodolide-L
Sridhar Musulla1,2, Y Bharathi Kumari2, Mahesh Madala2
1GVK Biosciences Private Limited, Nacharam, IDA Mallapur, Hyderabad, India.
Natural Product Research
|May 21, 2019
Abstract:
A new synthetic route for the total synthesis of dendrodolide-L has been developed from known chiral epoxides. The key reactions involved in this synthesis are regioselective ring-opening of epoxide, Yamaguchi esterification and ring-closing metathesis reactions (RCM) to result the target compound.
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