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Updated: Jan 24, 2026

Minimally-invasive Technique for Injection into Rat Optic Nerve
Published on: May 19, 2015
Variation of the minimally invasive CDCR technique
Austin Pharo1, James Chelnis2, Tara Goecks2
1LSU Eye Center, LSU Health Sciences Center New Orleans, New Orleans, LA, USA.
A new minimally invasive conjunctivodacryocystorhinostomy (miCDCR) technique using a specialized dilator offers a safe and quick alternative to traditional methods. This approach effectively resolves epiphora with a low complication rate, often avoiding general anesthesia.
Area of Science:
- Ophthalmology
- Surgical Innovation
- Oculoplastics
Background:
- Traditional (tCDCR) and endoscopic conjunctivodacryocystorhinostomy (eCDCR) are complex procedures with significant drawbacks.
- These traditional methods necessitate general anesthesia, facial incisions, and extensive osteotomies and mucosal flaps.
- Minimally invasive CDCR (miCDCR) techniques aim to simplify these surgical steps.
Purpose of the Study:
- To introduce and evaluate a novel variation of the miCDCR technique.
- This variation utilizes a Naugle-Fleming knurled dilator (NKD) for osteotomy creation and standard catheter kit instruments for Jones' tube placement.
- To assess the safety, efficacy, and outcomes of this modified miCDCR approach.
Main Methods:
- Retrospective chart review of patients undergoing the modified miCDCR technique between 2014 and 2016.
- Inclusion criteria: patients requiring primary or revision CDCR; Exclusion criteria: follow-up loss before six months.
- Primary endpoints included operative time, tube migration/complication rates, and epiphora cessation.
Main Results:
- Sixteen patients (19 cases) were reviewed, with an average age of 66.6 years.
- The procedure was performed under local/MAC with IV sedation in 62% of cases, avoiding general anesthesia.
- Average operative time was 17.4 minutes, with only one case (5%) requiring revision for tube migration; all patients achieved epiphora cessation.
Conclusions:
- The modified miCDCR technique is a safe and rapid surgical option for treating nasolacrimal duct obstruction.
- This technique can be effectively performed without general anesthesia, reducing patient risk and recovery time.
- The study demonstrates a low rate of tube migration and high success rate in resolving epiphora.
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