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Updated: Jan 24, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Stilbene Glycoside Oligomers from the Roots of Polygonum multiflorum
Shuo-Guo Li1,2,3, Xiao-Jun Huang1,2, Yuan-Lin Zhong1,2
1Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou, 510632, P. R. China.
Abstract:
Five new trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-d-glucopyranoside (TSG)-based stilbene glycoside oligomers (1-5) were isolated from the roots of Polygonum multiflorum. Their structures were elucidated by comprehensive spectroscopic analyses and chemical evidences. The absolute configurations of 1, 2, 4, and 5 were established by quantum-chemical electronic circular dichroism (ECD) calculations. Putative biosynthetic pathways of 1-5 were proposed using TSG as the key precursor. In addition, compounds 1 (multiflorumiside H) and 3 (multiflorumiside J) exhibited moderate inhibitory activities against NO production in LPS-stimulated RAW264.7 cells.
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