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Published on: June 12, 2020
Dietary Profiles, Nutritional Biochemistry Status, and Attention-Deficit/Hyperactivity Disorder: Path Analysis for a
Liang-Jen Wang1, Ya-Hui Yu2, Ming-Ling Fu3
1Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. wangliangjen@gmail.com.
Children with attention-deficit/hyperactivity disorder (ADHD) exhibit distinct nutritional biochemistry profiles. Unhealthy dietary patterns are linked to these deficiencies, suggesting diet management may improve ADHD symptoms.
Area of Science:
- Nutritional Biochemistry
- Pediatric Neurology
- Dietary Science
Background:
- Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder.
- Dietary habits and nutritional status are increasingly recognized as potential influencing factors in ADHD.
Purpose of the Study:
- To investigate the dietary and nutritional biochemistry profiles in children with ADHD.
- To explore the relationship between diet, nutritional status, and ADHD using path analysis.
Main Methods:
- Cross-sectional study involving 216 children with ADHD and 216 matched controls.
- Dietary intake assessed via Food Frequency Questionnaire (FFQ).
- Serum nutritional markers analyzed; Structural Equation Modeling (SEM) used to link diet, nutrition, and ADHD.
Main Results:
- ADHD children showed lower serum levels of vitamin B12, folate, vitamin B6, ferritin, and monounsaturated fatty acids (MUFA).
- ADHD group had higher serum saturated fatty acids (SFA), n-6/n-3 fatty acid ratio, and inorganic phosphorus.
- Children with ADHD consumed more nutrient-poor foods and less vegetables, fruits, and protein-rich foods.
Conclusions:
- Poor nutritional biochemistry profiles are associated with unhealthy dietary patterns in children with ADHD.
- Unhealthy diets may precede poor nutritional status, potentially contributing to ADHD.
- Dietary management and nutritional interventions should be considered for improving ADHD symptoms.
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