Chronic venous disease: from symptoms to microcirculation
Bernardo Senra Barros1, Stavros K Kakkos2, Marianne De Maeseneer3
1Laboratory of Clinical and Experimental Research on Vascular Biology (BioVasc), State University of Rio de Janeiro, Rio de Janeiro, Brazil - dots.br@gmail.com.
Summary
The 2018 European Venous Forum Guidelines emphasize early chronic venous disorder (CVD) symptoms and microcirculation changes. A combination of Ruscus, HMC, and Vitamin C is strongly recommended for symptom relief in CVD patients.
Area of Science:
- Vascular Medicine
- Phlebology
- Dermatology
Background:
- The 2018 European Venous Forum (EVF) Guidelines update management of lower limb chronic venous disorders (CVD).
- New guidelines incorporate early symptom recognition, microcirculation alterations, and re-evaluated veno-active drugs (VADs).
Purpose of the Study:
- To clarify the significance of early CVD symptoms and their relation to microcirculation.
- To guide the selection of appropriate VADs for individual CVD patients based on updated criteria.
Main Methods:
- Symposium discussion at the EVF annual meeting (June 28, 2018, Athens).
- Focused on three key questions regarding CVD symptoms, microcirculation, and VAD selection.
Main Results:
- Early symptoms indicate initial CVD stages; C0S patients require diagnosis and treatment.
- Microcirculation damage is an early indicator of venous disease onset.
- Ruscus+HMC+VitC demonstrated efficacy in RCTs.
Conclusions:
- Early diagnosis and treatment are crucial for patients presenting with initial CVD symptoms.
- Microcirculation alterations are primary indicators of developing venous disease.
- Ruscus+HMC+VitC is strongly recommended (Grade 1A) by 2018 EVF guidelines for managing CVD symptoms like pain, heaviness, swelling, paresthesia, and edema.
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