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Related Concept Videos

Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions03:03

Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions

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Unless individual gases chemically react with each other, the individual gases in a mixture of gases do not affect each other’s pressure. Each gas in a mixture exerts the same pressure that it would exert if it were present alone in the container. The pressure exerted by each individual gas in a mixture is called its partial pressure.
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Dalton's Law of Partial Pressure01:11

Dalton's Law of Partial Pressure

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The partial pressure of a gas is a measure of the thermodynamic activity of the gas's molecules. The pressure that a gas would create if it occupied the total volume available is called the gas's partial pressure. If two or more gases are mixed together in a container, the molecules move randomly and collide with each other, causing them to reach thermal equilibrium. When the gases have the same temperature, their molecules have the same average kinetic energy. Thus, each gas obeys the...
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Dosage Regimens: Partial Pharmacokinetic Parameters01:01

Dosage Regimens: Partial Pharmacokinetic Parameters

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It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
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Inverse z-Transform by Partial Fraction Expansion01:20

Inverse z-Transform by Partial Fraction Expansion

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The inverse z-transform is a crucial technique for converting a function from its z-domain representation back to the time domain. One effective method for finding the inverse z-transform is the Partial Fraction Method, which involves decomposing a function into simpler fractions with distinct coefficients. These fractions correspond to known z-transform pairs, facilitating the inverse transformation process.
To begin the process, the poles of the function are identified and the function is...
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Gas Exchange and Transport01:20

Gas Exchange and Transport

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Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.
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Homogeneous Equilibria for Gaseous Reactions02:15

Homogeneous Equilibria for Gaseous Reactions

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Homogeneous Equilibria for Gaseous Reactions
For gas-phase reactions, the equilibrium constant may be expressed in terms of either the molar concentrations (Kc) or partial pressures (Kp) of the reactants and products. A relation between these two K values may be simply derived from the ideal gas equation and the definition of molarity. According to the ideal gas equation:
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Related Experiment Video

Updated: Jan 24, 2026

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy ALPPS Procedure
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Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy ALPPS Procedure

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Laparoscopic Partial ALPPS: Much Better Than ALPPS!

Stéphanie Truant1, Mehdi El Amrani1, Clio Baillet2

  • 1Department of Digestive Surgery and Transplantation, Huriez Hospital, University of Lille, France.

Annals of Hepatology
|May 23, 2019
PubMed
Summary

Partial ALPPS (Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy) performed laparoscopically offers a less aggressive approach. This technique shows improved remnant liver function and volume gain, facilitating earlier second-stage surgery.

Keywords:
CancerLiverRegenerationScintigraphySurgery

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Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Medical Imaging

Background:

  • Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) is an option for unresectable colorectal liver metastases.
  • High morbidity and mortality rates are associated with the traditional ALPPS procedure.
  • Hepatobiliary scintigraphy aids in assessing patient eligibility and timing for ALPPS stages.

Observation:

  • A case series explored laparoscopic partial ALPPS (p-ALPPS) with a shortened first stage.
  • Sequential computed tomography (CT) volumetry and hepatobiliary scintigraphy (HIDA SPECT) assessed FRL.
  • Five patients underwent laparoscopic p-ALPPS, demonstrating rapid FRL hypertrophy.

Findings:

  • Laparoscopic p-ALPPS facilitated significant and rapid FRL functional volume gain.
  • This approach led to earlier second-stage hepatectomy with reduced inflammatory adhesions.
  • Results showed improved outcomes compared to standard ALPPS.

Implications:

  • Laparoscopic p-ALPPS appears feasible and less aggressive than standard ALPPS.
  • It may offer a viable alternative to portal vein embolization (PVE) and two-stage hepatectomy.
  • This technique could improve patient outcomes in managing extensive liver disease.