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VU6005806/AZN-00016130, an advanced M4 positive allosteric modulator (PAM) profiled as a potential preclinical

Darren W Engers1, Bruce J Melancon1, Allison R Gregro1

  • 1Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Bioorganic & Medicinal Chemistry Letters
|May 23, 2019
PubMed

Keywords:
M(4)Muscarinic acetylcholine receptorPharmacokineticsPositive allosteric modulator (PAM)Structure-activity relationship (SAR)

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