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Updated: Jan 24, 2026

A Generalized Method for Determining Free Soluble Phenolic Acid Composition and Antioxidant Capacity of Cereals and Legumes
Published on: June 10, 2022
Antioxidant properties of ALD grown nanoceria films with tunable valency
Ankur Gupta1, Tamil S Sakthivel2, Craig J Neal1
1Department of Materials Science and Engineering, University of Central Florida, 12760 Pegasus Blvd., P.O. Box 162450, Orlando, Florida 32816, USA. Sudipta.Seal@ucf.edu guptaankur@knights.ucf.edu and Advanced Materials Processing and Analysis Center, University of Central Florida, 4000 Central Florida Blvd., P.O. Box 162455, Orlando, Florida 32816, USA.
Abstract:
Herein, we provide the first account of a method to control cerium oxide's mixed valence states (as Ce3+ to Ce4+ ratio) in ultra-thin films formed via atomic layer deposition (ALD). It is determined that modulation of Ce3+/Ce4+ ratio occurs with respect to film thickness and is analogous to the change in surface chemistry observed for cerium oxide nanoparticles with varying particle diameter. The influence of film thickness on enzyme-mimetic radical scavenging is also characterized. Higher film thicknesses show 9-fold increase in catalytic activity. In vitro biocompatibility (apoptosis < 4%) and electrochemical biosensing (lowest concentration: 18 ppt) studies were performed to demonstrate the potential of ALD-grown nanoceria films for biomedical applications.
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