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Related Experiment Video

Updated: Jan 24, 2026

Studying Orthodontic Tooth Movement in Mice

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

Orthodontics and Genetics.

Alexandre R Vieira¹

¹Department of Oral Biology, School of Dental Medicine, University of Pittsburgh (Pittsburgh/PA, EUA).

Dental Press Journal of Orthodontics

|May 23, 2019

Summary

Genetics plays a role in malocclusions, but it

Area of Science:

Genetics and Developmental Biology
Orthodontics and Craniofacial Research

Background:

Genetic factors are implicated in the causes of malocclusions.
Previous research often assumed simple Mendelian inheritance patterns for malocclusions.

Purpose of the Study:

To explore the complex inheritance patterns of malocclusions.
To review research on genetic mechanisms influencing craniofacial growth deviations.

Main Methods:

Literature review of genetic and developmental studies on malocclusions.
Analysis of research on craniofacial growth and its genetic underpinnings.

Main Results:

Malocclusions exhibit a complex, multifactorial inheritance pattern.
Multiple genes contribute to the development of malocclusion phenotypes.

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Conclusions:

Malocclusions result from the interaction of multiple genes.
Environmental factors may also influence the development of malocclusions.