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Updated: Jan 24, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
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Relapsing polychondritis in human immunodeficiency virus.

Kelly Quinn1, Nektarios Lountzis2, Stephen M Purcell2

  • 1Dermatology and Skin Cancer Center, Red Bank, New Jersey, USA.

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|May 23, 2019
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Summary
This summary is machine-generated.

Relapsing polychondritis (RP), an autoimmune disease, is rarely seen in patients with human immunodeficiency virus (HIV). This case highlights RP in an HIV-positive individual without other autoimmune conditions, expanding understanding of immune dysregulation.

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Area of Science:

  • Rheumatology
  • Immunology
  • Infectious Diseases

Background:

  • Relapsing polychondritis (RP) is a rare autoimmune disorder affecting cartilage.
  • RP is often associated with immune dysregulation and other autoimmune conditions.
  • The association between RP and human immunodeficiency virus (HIV) infection is infrequently reported.

Observation:

  • This report details a case of relapsing polychondritis in a patient who is positive for HIV.
  • The patient had no other identifiable autoimmune diseases.
  • This presentation is unusual given the typical associations of RP.

Findings:

  • The case demonstrates that relapsing polychondritis can occur in HIV-positive individuals.
  • It suggests a potential link between HIV infection and the development of RP, even in the absence of other autoimmune diseases.
  • This finding broadens the spectrum of immune dysregulation associated with HIV.

Implications:

  • Clinicians should consider RP in the differential diagnosis of inflammatory conditions in HIV-positive patients.
  • Further research is warranted to explore the mechanisms underlying RP in the context of HIV infection.
  • This case contributes to understanding the complex interplay between viral infections and autoimmune phenomena.