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Updated: Jan 24, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Nail irregularities associated with Sézary syndrome
Katherine Park1, Jace Reed2, Rakhshandra Talpur3
1Department of Dermatology, Baylor College of Medicine; and Department of Dermatology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Abstract:
Sézary syndrome (SS) is the leukemic form of cutaneous T-cell lymphoma (CTCL) and can be associated with various nail irregularities, though they are infrequently reported. In this retrospective study, we reviewed medical records from a CTCL clinic database at the University of Texas MD Anderson Cancer Center (Houston, Texas) for reported nail abnormalities in patients with a diagnosis of SS. Findings for 2 select cases are described in more detail and are compared to prior case reports to establish a comprehensive list of nail irregularities that have been associated with SS.
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