Related Experiment Video
Updated: Jan 24, 2026

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
Published on: September 28, 2022
Near-Infrared Light Activates Molecular Nanomachines to Drill into and Kill Cells
Dongdong Liu, Víctor García-López, Richard S Gunasekera
1Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695-8204 , United States.
Abstract:
Using two-photon excitation (2PE), molecular nanomachines (MNMs) are able to drill through cell membranes and kill the cells. This avoids the use of the more damaging ultraviolet light that has been used formerly to induce this nanomechanical cell-killing effect. Since 2PE is inherently confocal, enormous precision can be realized. The MNMs can be targeted to specific cell surfaces through peptide addends. Further, the efficacy was verified through a controlled opening of synthetic bilayer vesicles using the 2PE excitation of MNM that had been trapped within the vesicles.
Related Concept Videos
Molecular Factors Affecting Cell Division
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
Molecular Models
Light Acquisition
Photoreceptors and Plant Responses to Light
Molecular and Ionic Solids
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
Molecular Orbital Theory II

