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Updated: Jan 24, 2026

Physiological Characterization of the Coral Holobiont Using a New Micro-Respirometry Tool
Published on: April 28, 2023
Labrenzbactin from a coral-associated bacterium Labrenzia sp
Amit Raj Sharma1, Tao Zhou1, Enjuro Harunari1
1Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama, 939-0398, Japan.
Abstract:
A new catecholate-containing siderophore, labrenzbactin (1), was isolated from the fermentation broth of a coral-associated bacterium Labrenzia sp. The structure and absolute configuration of 1 was determined by spectroscopic methods and Marfey's analysis. Overall, 1 showed antimicrobial activity against Ralstonia solanacearum SUPP1541 and Micrococcus luteus ATCC9341 with MIC values of 25 and 50 µg ml-1, respectively, and cytotoxicity against P388 murine leukemia cells with an IC50 of 13 µM.
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