Characterizing high-burden rosacea subjects: a multivariate risk factor analysis from a global survey

Area of Science:

• Dermatology
• Clinical Practice
• Patient-Reported Outcomes

Background:

• Rosacea is a common chronic inflammatory skin condition.
• Identifying patients with high-burden rosacea (HB) is crucial for targeted management.
• Current methods for identifying HB rosacea in clinical settings require further characterization.

Purpose of the Study:

• To identify specific features of rosacea that can help characterize high-burden (HB) subjects in clinical practice.
• To understand the factors associated with a high burden of rosacea.

Main Methods:

• A global online survey was conducted with rosacea patients from multiple countries.
• High-burden (HB) subjects were defined based on scores across four domains: quality of life, lifestyle adaptation, time trade-off, and willingness to pay.
• Multivariate-logistic modeling was employed to identify factors associated with HB.

Main Results:

• 158 out of 710 participants were identified as HB subjects.
• HB was present across all self-reported rosacea severity levels.
• HB subjects reported increased daily skincare time, double the impact on work productivity, and higher emergency room visit rates compared to non-HB subjects.
• Key factors associated with HB included rosacea severity, impact on daily activities, and age of symptom onset.

Conclusions:

• Rosacea comprises a distinct subset of high-burden (HB) patients.
• These HB subjects can be effectively identified using specific clinical and patient-reported characteristics.
• Characterizing HB rosacea is essential for optimizing patient care and resource allocation.