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Comparison of surgical field visibility during propofol or desflurane anesthesia for middle ear microsurgery
Xia Yuan1, Tingjie Liu1, Chunbo Hu1
1Department of Anesthesiology, The Eye, Ear, Nose and Throat Hospital, Fudan University, 83 fenyang road, Shanghai, 200031, China.
Background:
To compare surgical field visibility between patients given propofol/remifentanil (PR) or desflurane/remifentanil (DR) anesthesia.
Methods:
A total of 80 adult patients undergoing middle ear microsurgery due to cholesteatoma otitis media with American Society of Anesthesiologists physical status I and II were randomly assigned to the PR or DR groups. The depth of anesthesia was titrated to maintain a Bispectral index (BIS) between 40 and 50. Remifentanil was titrated to maintain the mean blood pressure within ±30% change of the pre-induction value. Surgical field visibility was rated at several timepoints by the surgeons using the Boezaart scores.
Results:
Average Boezaart scores for surgical field visibility at different time points were < 2 in both PR and DR groups. Surgical field visibility score was lower in the PR group than in the DR group. Requirement for remifentanil was higher in the PR group (850 (488/1330) μg) than in the DR group (258 (143/399) μg, P < 0.0001). The site effect concentration of remifentanil was higher in the PR group (3.6(2.8/5.0)ng/ml) than in the DR group (1.7 (1.0/1.6) ng/ml, P < 0.0001). Hemodynamic profile (i.e., heart rate and mean blood pressure) was similar between groups (P > 0.05). Extubation time (PR group, 21 min vs. DR group, 19 min; P = 0.199) and post-anesthesia care unit time (PR group, 37 min vs. DR group, 34 min; P = 0.324) were comparable between groups.
Conclusion:
Although PR anesthesia resulted in lower surgical field visibility scores than DR anesthesia, both groups had scores < 2, meaning no clinical differences between the two groups. DR provided acceptable operative conditions as well, albeit more remifentanil consumption was noted in the DR group.
Trial Registration:
China Clinical Research Information Service, ChiCTR-1,800,015,537 . Registered 5 April 2018. Date of enrolment of the first participant to the trial: 2 May 2018.
Insights
This study compared propofol/remifentanil (PR) and desflurane/remifentanil (DR) anesthesia for middle ear surgery. While DR offered slightly better surgical field visibility, both anesthesia types provided acceptable conditions with no significant differences in patient recovery.
Area of Science:
- Anesthesiology
- Surgical Outcomes
- Pharmacology
Background:
- Middle ear microsurgery for cholesteatoma otitis media requires optimal surgical field visibility.
- Evaluating anesthetic techniques that balance surgical conditions with patient safety is crucial.
Purpose of the Study:
- To compare surgical field visibility between propofol/remifentanil (PR) and desflurane/remifentanil (DR) anesthesia in patients undergoing middle ear microsurgery.
Main Methods:
- Eighty adult patients (ASA I-II) were randomized to PR or DR anesthesia.
- Anesthesia depth was monitored using Bispectral Index (BIS) (40-50).
- Surgical field visibility was assessed using Boezaart scores.
Main Results:
- Both PR and DR groups achieved average Boezaart scores below 2, indicating good visibility.
- Surgical field visibility scores were slightly lower in the PR group compared to the DR group.
- Remifentanil consumption and its effect-site concentration were significantly higher in the PR group.
Conclusions:
- While desflurane/remifentanil (DR) anesthesia demonstrated slightly superior surgical field visibility, both anesthetic regimens provided clinically acceptable operative conditions.
- The propofol/remifentanil (PR) group required significantly more remifentanil.
- No significant differences were observed in extubation or post-anesthesia care unit times between the groups.
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