Post-Ranibizumab injection endophthalmitis in aggressive posterior retinopathy of prematurity

Parijat Chandra1, Devesh Kumawat1, Ruchir Tewari1

  • 1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Insights

A preterm infant with aggressive retinopathy of prematurity developed endophthalmitis after ranibizumab injection. Prompt treatment with antibiotics and steroids, followed by vitrectomy, successfully saved the infant's eye.

Area of Science:

  • Ophthalmology
  • Neonatal Medicine
  • Infectious Diseases

Background:

  • Aggressive posterior retinopathy of prematurity (ROP) is a leading cause of blindness in premature infants.
  • Intravitreal injections, while effective for ROP, carry a risk of infectious complications like endophthalmitis.
  • This case highlights a rare but severe complication following ranibizumab treatment for ROP.

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