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Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
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[Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between

John Helmut Ramírez Cuentas1, Andrea Urtasun Erburu2, Mireia Roselló Guijarro2

  • 1Servicio de Pediatría, Hospital Quirón, Valencia, España; Servicio de Pediatría, Centro de Salud de Gandía, Gandía, Valencia, España.

Anales De Pediatria
|May 27, 2019
PubMed

Insights

Paediatric malaria remains prevalent due to immigration and travel. Early diagnosis and treatment are crucial for favourable outcomes in children with malaria.

Area of Science:

  • Infectious Diseases
  • Paediatric Medicine
  • Tropical Medicine

Background:

  • Malaria is a significant cause of infant mortality globally.
  • Recent immigration and international travel contribute to malaria prevalence in non-endemic regions.
  • Prompt recognition of malaria is vital in febrile children with relevant travel history.

Purpose of the Study:

  • To analyze paediatric malaria cases treated at La Fe Hospital, Valencia, from 1993 to 2015.
  • To describe the epidemiological characteristics, clinical presentation, and treatment outcomes of childhood malaria.
  • To highlight the importance of considering malaria in the differential diagnosis of febrile children.

Main Methods:

  • Retrospective and descriptive study design.
  • Inclusion of all paediatric malaria cases (under 15 years) confirmed and treated.
  • Data collection on patient demographics, origin, prophylaxis, causative species, complications, and treatment.

Main Results:

  • 54 paediatric malaria cases were identified between 1993 and 2015.
  • The majority of cases originated from Equatorial Guinea, with Plasmodium falciparum being the most common species.
  • While 13% of patients had complicated malaria, all cases showed a favourable clinical response with no reported deaths or significant side effects.

Conclusions:

  • Paediatric malaria continues to be a relevant public health issue, influenced by migration patterns.
  • Effective treatment strategies led to universally positive clinical responses.
  • Malaria should be strongly suspected in febrile children with a history of travel to or residence in endemic areas.
Abstract

Keywords:
EspañaMalariaPaediatricsPediatríaSpain

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