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Updated: Jan 24, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
Our eight years experience in postintubation/posttracheostomy tracheal stenosis
Mehmet Akif Özgül1, Şule Gül1, Erdoğan Çetinkaya1
1Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey.
Tracheal stenosis, often caused by intubation or tracheostomy, has various treatment options. Endoscopic interventions offer an alternative for inoperable patients, but follow-up is crucial due to potential complications and restenosis.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Interventional Bronchoscopy
Background:
- Tracheal stenosis (TS) commonly results from post-intubation or post-tracheostomy trauma.
- Bronchoscopy is the standard for diagnosing tracheobronchial pathology.
- Multiple treatment modalities exist for managing TS.
Purpose of the Study:
- To review treatment options for tracheal stenosis patients.
- To analyze the follow-up outcomes of these treatments.
Main Methods:
- A retrospective review of 110 consecutive patients with TS between 2009 and 2018.
- Data collected included demographics, stenosis characteristics, treatment techniques, complications, and survival.
- All patients underwent mechanical dilatation; some received bronchoscopic resection or tracheal stents.
Main Results:
- The study included 110 patients (49.1% female, mean age 53.7 years).
- Complex stenosis was most common (74.5%).
- 32.7% of patients underwent surgical resection during follow-up, with 16.7% mortality, 47.2% recovery, and 36.1% restenosis.
Conclusions:
- Tracheal stenosis management involves diverse modalities, frequently arising post-intubation/tracheostomy.
- While surgery is often preferred, endoscopic interventions are viable for inoperable patients.
- Post-interventional follow-up is essential to monitor for complications and restenosis.
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