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Updated: Jan 24, 2026

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
Published on: December 21, 2021
Maternal Selenium and Developmental Programming
Athanasios C Pappas1, Evangelos Zoidis2, Stella E Chadio3
1Department of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece. apappas@aua.gr.
Abstract:
Selenium (Se) is an essential trace element of fundamental importance to health due to its antioxidant, anti-inflammatory, and chemopreventive properties, attributed to its presence within at least 25 selenoproteins (Sel). In this review, we describe some of the recent progress, in our understanding, on the impact of maternal Se intake during the periconceptional period on offspring development and health. Maternal nutrition affects the performance and health of the progeny, and both maternal and offspring Se supplementations are essential for the optimal health and antioxidant protection of the offspring. The case of Se in epigenetic programming and early life nutrition is also discussed.
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