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Updated: Jan 24, 2026

Author Spotlight: Exploring the Role of FAM83A in Cervical Cancer
Published on: February 9, 2024
A case of aortitis during cisplatin-based chemotherapy for cervical cancer
Katharine Webb1, Vineet Prakash1, Othman Kirresh1
1St Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, UK.
Abstract:
A case of aortitis in a patient undergoing adjuvant cisplatin and topotecan chemotherapy for cervical cancer following presentation with pyrexia of unknown origin and raised inflammatory markers is presented. Although many chemotherapy agents are known to cause small vessel vasculitis and there are several reported cases of large vessel vasculitis following gemcitabine chemotherapy, there is only one previously described case of aortitis following cisplatin administration. This case is presented with corresponding CT and 18F-FDG PET-CT imaging with discussion of the literature regarding vasculitis and chemotherapy.
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