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Published on: June 30, 2016
Disseminated Central Nervous System Histoplasmosis: A Case Report
Hector H Gonzalez1, Manas Rane1, Anthony Cioci1
1Internal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Abstract:
Central nervous system (CNS) histoplasmosis is a rare manifestation of disease, often misdiagnosed due to the wide spectrum of neurological presentation. We present a rare case of CNS histoplasmosis in a 62-year-old male with untreated myeloproliferative disease who presented with altered mental status. This case emphasizes the clinical presentation and diagnostic difficulty in a patient with CNS histoplasmosis. We also highlight the importance of implementing a multidisciplinary approach in the medical management of disseminated histoplasmosis with CNS involvement.
Insights
Central nervous system (CNS) histoplasmosis is a rare but serious fungal infection. Early diagnosis and a multidisciplinary approach are crucial for managing this challenging condition, especially in immunocompromised patients.
Area of Science:
- Mycology
- Infectious Diseases
- Neurology
Background:
- Central nervous system (CNS) histoplasmosis is an uncommon complication of disseminated Histoplasma capsulatum infection.
- It often presents with diverse neurological symptoms, leading to frequent misdiagnosis.
- Patients with underlying conditions like myeloproliferative disease are at increased risk.
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