Related Experiment Video
Updated: Jan 24, 2026

Recordings of Neural Circuit Activation in Freely Behaving Animals
Published on: July 22, 2009
Microglia: Lifelong modulator of neural circuits
Ako Ikegami1, Koichiro Haruwaka1, Hiroaki Wake1,2
1Division of System Neuroscience, Kobe University Graduate School of Medicine, Kobe, Japan.
Abstract:
Microglia, the sole immune cells in the brain, are the key player for synaptic regulation required for our brain function in both developing and adult brain. They have highly motile processes to detect synaptic functions. Recent accumulated studies have unveiled the mechanism underlying synapse detection and pruning / formation by microglia. In this review, we summarize the current knowledge of various microglial machinery recruited in synaptic modulation in the different life stages and contexts.
Related Concept Videos
Neural Circuits
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Second-Order Circuits
Input signals typically originate from voltage or current sources, with the output often representing voltage across the capacitor and/or current through the inductor. For example, in...
First-Order Circuits
One common example of a first-order circuit is the RC (resistor-capacitor) circuit. These circuits are used in relaxation oscillators such as neon lamp oscillator circuits. When voltage is...
The Y-to-Y Circuit
LC Circuits
Three-Phase Circuits

