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Updated: Jan 24, 2026

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
Published on: February 2, 2022
Multiparametric Functional Magnetic Resonance Imaging for Evaluating Renal Allograft Injury
Yuan Meng Yu1, Qian Qian Ni2, Zhen Jane Wang3
1Department of Medical Imaging, Jinling Hospital, Clinical School of Southern Medical University, Nanjing, China.
Abstract:
Kidney transplantation is the treatment of choice for patients with end-stage renal disease, as it extends survival and increases quality of life in these patients. However, chronic allograft injury continues to be a major problem, and leads to eventual graft loss. Early detection of allograft injury is essential for guiding appropriate intervention to delay or prevent irreversible damage. Several advanced MRI techniques can offer some important information regarding functional changes such as perfusion, diffusion, structural complexity, as well as oxygenation and fibrosis. This review highlights the potential of multiparametric MRI for noninvasive and comprehensive assessment of renal allograft injury.
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