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F Herms1

  • 1Service de dermatologie, CHU Saint-Louis, 1 avenue Claude-Vellefaux, 75010 Paris, France.

Annales De Dermatologie Et De Venereologie
|May 29, 2019
PubMed
Summary
This summary is machine-generated.

Actinic keratoses (AK) management involves various treatments for individual lesions or field cancerization. Physicians must consider patient factors and costs, as patients with AK have a high risk of developing skin cancer.

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Actinic keratoses (AK) are common skin lesions resulting from sun damage.
  • Field cancerization describes sun-damaged skin prone to developing new AK and skin cancers (SC).

Purpose of the Study:

  • To review therapeutic options for actinic keratoses (AK).
  • To discuss management strategies for individual lesions and field cancerization.
  • To highlight the importance of regular skin examinations for patients with AK.

Main Methods:

  • Review of instrumental and medical treatment options for AK.
  • Discussion of side-effects, patient compliance, and cost-effectiveness.
  • Emphasis on histological examination for treatment resistance or atypical symptoms.

Main Results:

Keywords:
Actinic keratosisCarcinome cutanéChamp de cancérisationField cancerizationKératose actiniqueSkin carcinoma

Related Experiment Videos

  • Cryotherapy is common for isolated AK.
  • Photodynamic therapy (PDT), 5-fluorouracil (5-FU), imiquimod, ingenol mebutate, and diclofenac are used for extensive AK and field cancerization.
  • Local side-effects include pain, irritation, erythema, edema, and scars.

Conclusions:

  • No single randomized comparative study exists for all AK treatments.
  • Treatment choice depends on clinical factors, patient compliance, side-effects, and cost.
  • Patients with AK require regular full-body examinations due to high skin cancer risk.